2021.10.28 14:39 lllDUNN It's too long and I can't pronounce it
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2021.10.28 14:39 culture__vulture Dear Family: Methadone
The work I do involves patients constantly asking me what they can say to their parents, husbands, wives, girlfriends, boyfriends, brothers, sisters, employers, etc. who are anti-MMT and poisoned by the stigma associated with MMT. So my people at NAMA created this “letter to family” document that is very helpful for any of you who might want to convince someone you know that they’re wrong for being anti-methadone. Feel free to share it:
This letter will attempt to address some common concerns of those of you who have loved ones on Methadone or Buprenorphine (Suboxone/Subutex) Maintenance Treatment for opioid addiction. There are many misconceptions and common misunderstandings surrounding these treatments, which education and knowledge about the treatment may alleviate.
Methadone, while one of the most extensively studied treatments, is unfortunately surrounded by misinformation, unfair stigma and prejudice based on fears and assumptions. Family members quite naturally are concerned about their loved one's health and future and want the best for them, and they may have heard some things about MAT (Medication Assisted Treatment) that cause them alarm.
One of the most commonly voiced concerns is that MAT is "just trading one addiction for another.” Many feel that the only way to truly recover from addiction is to abstain from all mood altering substances. At one time this was thought by most to be true. However, science has discovered that with long term opiate addiction, the brain's natural production of endorphins is shut down.
Endorphins are the chemicals we all have that enable us to feel pleasure and happiness. We all have opiate receptors in our brains for these chemicals to attach to. The word “endorphin" comes from the words "endogenous” (internal origin) and "morphine.” These chemicals are released when we eat delicious food, enjoy a beautiful sunset, exercise (runner's high), or are released as natural painkillers when we are injured.
Without this natural chemical, life can be very difficult, and this is hard for those people who do not have this lack of endorphin production to understand. When we flood our systems with exogenous (external) opiates such as heroin, our bodies recognize that we have plenty available and subsequently stop manufacturing endorphins naturally. So once the patient runs out of the opiate/opioid, they have almost zero endorphins available. This is precisely what causes withdrawal. Essentially the opposite of the high—severe depression, loss of motivation, irritability, insomnia, anxiety, rapid heart rate, diarrhea, nausea, cold sweats, muscle cramps, severe aches, etc.
This happens to all opiate/opioid abusers when they cease taking opiates, the extent or degree varying person to person. Some patients, especially those with short term addiction histories, will be able to get their natural endorphins back into good working order after a few weeks or months of abstinence and will begin to gradually improve.
However, for many, the damage done is permanent. This has been demonstrated in many scientific studies involving CT scans of the addicted brain. For these patients, no amount of abstinence, counseling, group therapy, will power, or good intentions will undo the fact that their brains simply will no longer produce endorphins in sufficient quantity to enable them to live a normal, happy life.
This is, in fact, very similar to the way in which diabetics require supplemental insulin because their pancreas no longer manufactures insulin. In addition, there are some patients who have never had a normally functioning endorphin system, who have struggled since birth with crippling depression, and who became addicts in an effort to relieve their constant emotional and mental misery. Abstinent recovery works poorly or not at all for these people as well.
This is where MAT comes in.
Methadone (and Buprenorphine, aka Suboxone or Subutex) are synthetic opioids, used to treat addiction. Methadone has some unusual properties that make it well suited to treat addiction. It has a very long half-life (long-acting, remaining active in the tissues for up to 72 hours after ingestion). It does not cause the “high”(euphoria) caused by short-acting opiates like heroin because it is slowly metabolized by the liver, reaching the brain slowly.
In fact, many overdoses involving this drug are due to people seeking the high they have come to expect from other opiates but are not getting it, so they take more and more. A stable methadone patient who is not mixing the medication with other drugs--particularly benzodiazepines, which can sometimes be a very dangerous mixture--and who is on a medically appropriate dose will not be "high" or sedated at all. These patients are able to work, operate a vehicle, care for children, and do anything else a normal person can do.
Their minds are not "clouded.” Some of these rumors may come from observing patients who are abusing other drugs with their methadone or buprenorphine, or are taking more than prescribed. Methadone and Buprenorphine, taken as prescribed, balance the chemicals in the brain so that the patient feels normal.
Unfortunately, standard antidepressants generally do not work well for those with dysfunctional endorphin systems because they target serotonin rather than endorphins. These treatments are also unique in that they do not attach to every opiate receptor in the brain, leaving some open to encourage production of natural endorphins, if possible. This contributes to the healing of the addicted brain.
Methadone and Buprenorphine are commonly referred to as “replacement drugs” or “replacing one addiction for another,” which is not accurate. In fact, Methadone & Buprenorphine replace the natural endorphins no longer manufactured naturally by the patient's brain, in the same way that synthetic insulin supplements the pancreas’ own natural production of insulin, if any at all is still naturally produced.
Methadone and Buprenorphine treatment enables the patient to return to a normal, productive, law-abiding life in 60-90% of cases, and even when the patient continues abusing other drugs, etc, it may lower their chances of contracting a disease by reducing their drug use, and enables them to see a medical professional for assistance and referrals on a daily basis.
However, for many (not all) MAT patients, long term therapy--even lifelong--may be needed to maintain recovery. Addiction is a chronic, incurable disease. We do not tell diabetics, blood pressure patients, and epileptics to discontinue their medications because we know that if they do, the active disease will return. Why, then, do we encourage recovering, thriving MAT patients to do so, when the relapse rates for those discontinuing MAT is greater than 90%?
MAT with methadone or buprenorphine is the most effective modality of treatment for opiate addiction available today--far more effective than traditional rehabs, 12 step groups and abstinence alone. By no means is it the treatment of choice for every opiate addict. However, if abstinent methods have failed many times over, there is little point in continuing to try the same thing expecting different results.
Most experts recommend that a patient remain in maintenance treatment a MINIMUM of 2-3 years after they cease illicit drug use. At that time, if—and only if—the PATIENT themselves wishes to begin a taper regimen, one can be attempted. Tapering must be done on a slow and gradual basis--no more than 10% of the dose every 3-4 weeks, and some patients may require smaller decreases and longer time in between decreases. If the person begins experiencing severe cravings or withdrawals, they should stop and return to an adequate dose until symptoms subside.
If the person relapses, this should not be seen as failure or weakness, but only as evidence that they may require ongoing therapy to control their symptoms. Family support is ESSENTIAL to the patient's successful recovery on MAT, and continued questions like "When are you going to get off that stuff? It's just a crutch!" undermine treatment efforts and sabotage recovery, leaving the patient confused, sad and frustrated instead of feeling proud and happy at the improvements in their lives. Addiction is a deadly disease and there are few effective treatments for it, so please support your loved one's recovery efforts and praise them when you see improvements. There is nothing positive to be gained by forcing them off treatment solely due to stigma before they are ready.
If you would like more information about MAT, please seek out reputable sources such as SAMHSA (Substance Abuse and Mental Health Services Administration) at www.samhsa.gov; AATOD (the American Association for the Treatment of Opioid Dependence) at www.aatod.org; or the National Alliance for Medication Assisted Recovery (NAMA-R) at www.methadone.org
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2021.10.28 14:39 ChrispyChicken00 Need accountability
Hello everyone, I've struggled with BED for a long time now. I am making this post to hold myself accountable for today, in the hopes that anyone sees this. I will not give in today. I will report back tomorrow. Thank you
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2021.10.28 14:39 snakeheads0 Celtics Podcast
Hey all, I've been trying to do some research on a podcast to listen to about the Celtics and most of the podcasts I've listened to are saying the similar things week to week. It feels like I'm living in an echo chamber where no one has a unique side of the story or just anything special to draw me into their podcast specifically. Does anyone know of a podcast that just hits it out of the park with their production, analysis, and makes a their podcast more than just a normal podcast? Any suggestions help, thanks all
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2021.10.28 14:39 stawrberry Found these in my dad’s storage today 🤗 another great find
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2021.10.28 14:39 matthewlepoire Breaking Biotech - 102 - Arvinas' PIONEERING PROTAC Tech to Enhance Cancer Outcomes | Interview with CEO John Houston
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2021.10.28 14:39 FrontpageWatch2020 [#326|+1055|504] Because I’m bored, pick a number and I respond [r/BisexualTeens]
2021.10.28 14:39 Alliturtle What make Call of Cthulu a better mystery/investigation game than dnd?
The saying goes that "dnd isnt well suited for running mystery and investigation stories" or that "dnd is about killing monsters." Now, I've only got cursory familiarity with Call of Cthulu but I've heared it's far more a game about investigating and unraveling a mystery.
Obviously some combination of good GM and good players can may any game, any playstyle good, but if we're just talking game and system mechanics, what sets call of cthulu apart from dnd that makes it a better system for investigation? Are there specific mechanisms or is it just down to the tone that tends to come with the setting and common play styles?
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2021.10.28 14:39 Ketomealsandrecipes Keto Dairy Free Coconut Burfi - Keto Coconut Fudge
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2021.10.28 14:39 whuuz Can Nicki Minaj use the N word?
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submitted by KaleAway6968 to CryptoMars [link] [comments]
2021.10.28 14:39 Gyrskogul Bought my first house a couple weeks ago, today the gf got started on our plant wall :)
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2021.10.28 14:39 cameron5769 Perfectly timed screenshot from str goku and vegeta’s SA
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2021.10.28 14:39 Ishaan863 Lirik makes a mistake
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2021.10.28 14:39 NavyCobra1417 From a Floatplane extras vid
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2021.10.28 14:39 andylugz15 Which beach boy would be most likely to survive alone in the wilderness?
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2021.10.28 14:39 jtn_92 Want to install a Stealth hitch.
I’d like to put a stealth hitch on my macan but obviously the dealership won’t and another garage that services Porsches would only install a factory one even if I ordered it myself. How hard are they to install in a regular garage? And they mentioned reprogramming something after the wiring is installed. Can I Install the hitch without the trailer light connection? There’s a very small chance I ever pull a trailer with this car, mostly a bike or cargo rack. Also if anyone has had one how do they hold up? Where I live roads are bumpy/ shitty.
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2021.10.28 14:39 SchulBones Watch Congress grill Big Oil Execs (C-Span) 10/28/2021
2021.10.28 14:39 lurkerlurker789 Meet Cain
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2021.10.28 14:39 Mr_Fanntastic Looking for advice on this gaming PC
Been a console player my entire life and want to dive into the world of PC gaming. Since I do not have much knowledge about PC gaming, I am looking for advice. After doing some research here and a few other places, I have configured this HP Omen. Will this do the job? Looking to play at 1440P and higher. Mostly play RPGs and FPSs. This will be 99% gaming computer. The other 1% will be uploading pictures and browsing the internet. The budget is $2,000 to $2,500.
I configured an HP Omen 30L with AMD 5600X, 16GB RAM, 512 SSD, RTX 3080, 800W power supply. This comes out to about $2.1K. With coupons, I can get this down further. Is this sufficient? Any advice? Better options or builds?
Thanks for the help.
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2021.10.28 14:39 olivetreeportal A rainy fall day in our apartment 😍
2021.10.28 14:39 whatwouldgrapeapedo You'd think someone with organ transplants would keep safe, but he hated masks, Fauci, and the Libs more. Jimmy is nominated.
2021.10.28 14:39 madoughna Is it still good time to buy LCID or wait a bit to go down?
2021.10.28 14:39 Kevbray Me encontré esta joya
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